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We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment. Storage Medications which contain A2+ may decrease Norvasc effect. Non-steroid anti-inflammatory medications and estrogens may decrease effectiveness of Norvasc. Diuretics may increase Norvasc activity. Concomitant taking with medications containing lithium might aggravate their toxicity. Do not take this drug if it was not administered to you. Follow all directions of your doctor. It is possible to take Norvasc with or without food. As it is metabolized in liver it should be administered cautiously in patients with liver failure. Drug interaction The most common side effects are edema of lower extremities and headache. 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